PUBLICATIONS

Both neighborhood and individual-level social cohesion are associated with testing for HIV in Southeastern Pennsylvania adult population

Authors: Gamble-George, J., Hayashi, K., Dean, L.T., Villalonga-Olives, E., Martinez, I., and Ransome, Y.
Published: 2025 in Annals of Epidemiology, 108:106-115
DOI: 10.1016/j.annepidem.2025.06.013
PMID: 40578713

Empowering the biomedical research community: Innovative SAS deployment on the All of Us Researcher Workbench

Authors: Humes, I., Shyr, C., Dillon, M., Liu, Z., Peterson, J., St Jeor, C., Malkes, J., Master, H., Mapes, B., Azuine, R., Mack, N., Abdelbary, B., Gamble-George, J., Goldmann, E., Cook, S., Choupani, F., Baskir, R., McMaster, S., Lunt, C., Watson, K., Lee, M., Schwartz, S., Munshi, R., Glazer, D., Banks, E., Philippakis, A., Basford, M., Roden, D., and Harris, P.A.
Published: 2024 in Journal of the American Medical Informatics Association, 31(12):2994-3000
DOI: 10.1093/jamia/ocae216
PMID: 39135439

Racial and ethnic differences in the association of social cohesion and social capital with HIV testing

Authors: Ransome, Y., Hayashi, K., Gamble-George, J., Dean, L.T., and Villalonga-Olives, E.
Published: 2023 in SSM - Population Health, 21:101327
DOI: 10.1016/j.ssmph.2022.101327
PMID: 36618543

Alcohol Use Cravings as a Mediator Between Associated Risk Factors on Increased Alcohol Use among Youth Adults in New York During the COVID-19 Pandemic

Authors: Opara, I., Malik, S., Lardier Jr., D.T., Gamble-George, J., Kelly, R.J., Okafor, C.N., Greene, R.N., and Parisi, D.
Published: 2021 in Alcoholism Treatment Quarterly, 39(4):415-429
DOI: 10.1080/07347324.2021.1950091
PMID: 34898835

In Parkinson's patient-derived dopamine neurons, the triplication of α-synuclein locus induces distinctive firing pattern by impeding D2 receptor autoinhibition

Authors: Lin, M., Mackie, P.M., Shaerzadeh, F., Gamble-George, J.C., Miller, D.R., Martyniuk, C.J., and Khoshbouei, H.
Published: 2021 in Acta Neuropathologica Communications, 9(1):107
DOI: 10.1186/s40478-021-01203-9
PMID: 34099060

HIV-1 Tat regulation of dopamine transmission and microglial reactivity is brain region specific

Authors: Miller, D.R., Shaerzadeh, F., Phan, L., Sharif, N., Gamble-George, J., McLaughlin, J.P., Streit, W.J., and Khoshbouei, H.
Published: 2018 in Glia, 00:1-14
DOI: 10.1002/glia.23447
PMID: 29733459
PMCID: PMC6185750

Cyclooxygenase-2 inhibition reduces stress-induced affective pathology

Authors: Gamble-George, J.C., Baldi, R., Halladay, L., Kocharian, A., Silva, C., Roberts, H., Haymer, A., Marnett, L.J., Holmes, A., and Patel, S.
Published: 2016 in eLife, 5:e14137
DOI: http://dx.doi.org/10.7554/eLife.14137
PMID: 27162170
PMCID: PMC4862754

Multiple mechanistically distinct modes of endocannabinoid mobilization at central amygdala glutamatergic synapses

Authors: Ramikie, T.S., Niyles, R., Bluett, R.J., Gamble-George, J.C., Hartley, N.D., Mackie, K., Watanabe, M., Katona, I, and Patel, S.
Published: 2014 in Neuron, 81(5):1111-1125
DOI: 10.1016/j.neuron.2014.01.012
PMID: 24607231
PMCID: PMC3955008

Chronic Methamphetamine Increases Alpha-Synuclein Protein Levels in the Striatum and Hippocampus but not in the Cortex of Juvenile Mice

Authors: Butler, B., Gamble-George, J., Prins, P., North, A., Clarke, J.T., Khoshbouei, H.
Published: 2014 in Journal of Addiction & Prevention, 2(2):pii: 6
PMID: 25621291
PMCID: PMC4303106

Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation

Authors: Bluett, R.J.*, Gamble-George, J.C.*, Hermanson, D. J., Hartley, N.D., Marnett, L. J., and Patel, S.  *These authors contributed equally to the manuscript
Published: 2014 in Translational Psychiatry, 4:e408
DOI: 10.1038/tp.2014.53
PMID: 25004388
PMCID: PMC4119220

Substrate-selective inhibition of COX-2 enhances central endocannabinoid signaling

Authors: Hermanson, D.J., Hartley, N.D., Gamble-George, J., Brown, N., Shonesy, B.C., Kingsley, P.K., Colbran, R.J., Reese, J., Marnett, L.J., and Patel, S.
Published: 2013 in Nature Neuroscience, 16(9):1291-8
DOI: 10.1038/nn.3480
PMID: 24845457
PMCID: PMC4074568

Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing, and stress-reactivity

Authors: Gunduz-Cinar, O., MacPherson, K.P., Cinar, R., Gamble-George, J., Sugden, K., Williams, B., Godlewski, G., Ramikie, T.S., Gorka, A.X., Alapafuja, S.O., Makriyannis, A., Poulton, R., Patel, S., Hariri, A.R., Caspi, A., Moffitt, T.E., Kunos, G., and Holmes, A.
Published: 2013 in Molecular Psychiatry, 18(7):813-23
DOI: 10.1038/mp.2012.72
PMID: 22688188
PMCID: PMC3549323

Dissociable effects of CB1 receptor blockade on anxiety-like and consummatory behaviors in the novelty-induced hypophagia test

Authors: Gamble-George, J.C., Conger, J.R., Hartley, N.D., Gupta, P., Sumislawski, J.J., and Patel, S.
Published: 2013 in Psychopharmacology (Berl), 228(3):401-9
DOI: 10.1007/s00213-013-3042-8
PMID: 23483200
PMCID: PMC3707973

Chronic methamphetamine exposure produces a delayed, long-lasting memory deficit

Authors: North, A.*, Swant, J.*, Salvatore, M. F., Gamble-George, J., Prins, P., Butler, B., Mittal, M. K., Clark, J., Hasting, R., Khoshbouei H.  *These authors contributed equally to the manuscript
Published: 2013 in Synapse, 67(5):245-57
DOI: 10.1002/syn.21635
PMID: 23280858
PMCID: PMC3831527

α-Synuclein stimulates a dopamine transporter-dependent chloride current and modulates the activity of the transporter

Authors: Swant, J., Goodwin, J.S., North, A., Ali, A.A., Gamble-George, J., Chirwa, S., and Khoshbouei, H.
Published: 2011 in Journal of Biological Chemistry, 286(51):43933-43
DOI: 10.1074/jbc.M111.241232
PMID: 21990355
PMCID: PMC3243541

Sorafenib inhibits nuclear factor kappa B, decreases inducible nitric oxide synthase, and cyclooxygenase-2 expression, and restores working memory in APPswe mice

Authors: Echeverria, V., Burgess, S., Gamble-George, J., Zeitlin, R., Lin, X., Cao, C., and Arendash, G.W.
Published: 2009 in Neuroscience, 162(4):1220-1231
DOI: 10.1016/j.neuroscience.2009.05.019
PMID: 19447162

Raf inhibition protects cortical cells against β-amyloid toxicity

Authors: Echeverria, V., Burgess, S., Gamble-George, J., Arendash, G.W., and Citron, B.A.
Published: 2008 in Neuroscience Letters, 444(1):92-96
DOI: 10.1016/j.neulet.2008.07.092
PMID: 18706973

Recruitment and retention strategies for improving representation in clinical research: A meta-synthesis

Authors: Peters, C.J.*, Greve, J.M.*, Karbasi, A.**, Walker, M.**, Adesanya, L.**, Gamble-George, J.**, Redmond, N., Adjei, B., and Olufemi, O. *These authors contributed equally to the manuscript. **These authors contributed equally to the manuscript.
Published: 2025 in PLoS One, 20(6):e0322796
DOI: 10.1371/journal.pone.0322796
PMID: 40549693
PMCID: PMC12184919

HIV-Related Stigma Research as a Priority at the National Institutes of Health

Authors: Greenwood, G.L., Wilson, A., Bansal, G.P., Barnhart, C., Barr, E., Berzon, R., Boyce, C.A., Elwood, W., Gamble-George, J., Glenshaw, M., Henry, R., Lida, H., Jenkins, R.A., Lee, S., Malekzadeh, A., Morris, K., Perrin, P., Rice, E., Sufian, M., Weatherspoon, D., Whitaker, M., Williams, M., Zwerski, S., and Gaist, P.
Published: 2021 in AIDS and Behavior, 26(Suppl 1):5-26
DOI: 10.1007/s10461-021-03260-6
PMID: 33886010

Maternal Morbidity and Mortality: Are We Getting to the "Heart" of the Matter?

Authors: Varagic, J., Desvigne-Nickens, P., Gamble-George, J., Hollier, H., Maric-Bilkan, C., Mitchell, M., Pemberton, V.L., and Redmond, N.
Published: 2020 in Journal of Women's Health, 30(2):178-186
DOI: 10.1016/j.pcad.2020.03.006
PMID: 33259740

ImPlementation REsearCh to Develop Interventions for People Living with HIV (the PRECluDE consortium): Combatting chronic disease comorbidities in HIV populations through implementation research

Authors: Gamble-George, J.C., Longenecker, C.T., Webel, A.R., Au, D.H., Brown, A.F., Bosworth, H., Crothers, K., Cunningham, C.E., Fiscella, K.A., Hamilton, A.B., Helfrich, C.D., Ladapo, J.A., Luque, A., Tobin, J.N., Wyatt, G.E., and for the Implementation Research to Develop Interventions for People Living with HIV (PRECluDE) Consortium
Published: 2020 in Progress in Cardiovascular Diseases, 63(2):79-91
DOI: 10.1016/j.pcad.2020.03.006
PMID: 32199901
PMCID: PMC7237329

HIV, Tat and dopamine transmission

Authors: Gaskill, P.J., Miller, D.R., Gamble-George, J., Yano, H., and Khoshbouei, H.
Published: 2017 in Neurobiology of Disease, 105:51-73
DOI: 10.1016/j.nbd.2017.04.015
PMID: 28457951
PMCID: PMC5541386

Substrate-selective COX-2 inhibition as a novel strategy for therapeutic endocannabinoid augmentation

Authors: Hermanson, D.J., Gamble-George, J.C., Marnett, L.J., and Patel, S.
Published: 2014 in Trends in Pharmacological Sciences, 35(7):358-67
DOI: http://dx.doi.org/10.1016/j.tips.2014.04.006
PMID: 24845457
PMCID: PMC4074568

Letter by Gamble-George et al Regarding Article, "Identification of Racial Inequities in Access to Specialized Inpatient Heart Failure Care at an Academic Medical Center"

Authors: Gamble-George, J.C., Redmond, N., and Boyce, C.A.
Published: June 5, 2020 in Circulation: Heart Failure
DOI: 10.1161/circheartfailure.120.007171
PMID: 32498622

Substrate-selective COX-2 Inhibition Decreases Anxiety via Endocannabinoid Activation

Authors: Hermanson, D. J., Gamble-George, J., Marnett, L. J., and Patel, S.
Published: May 1, 2014 in Biological Psychiatry, 75(9): S274
DOI: 10.1016/j.biopsych.2014.03.015

Planning and Development of Human Resources in Africa - Practical Approaches

Authors: Asilia, P. and Gamble-George, J.
Published: April 2012 in 13th World Congress on Public Health – Towards Global Health Equity: Opportunities and Threats, Ethiopian Public Health Association, Addis Ababa, Ethiopia
DOI: https://bit.ly/3c0d5Fd

Methamphetamine exposure affects α-synuclein expression in the cortex

Authors: Gamble-George, J.C. and Khoshbouei, H.
Published: April 1, 2011 in The FASEB Journal, 25(S1): 1005.2
DOI: 10.1096/fasebj.25.1_supplement.1005.2

Sorafenib as a therapeutic agent against Alzheimer's disease

Authors: Echeverria Moran, V., Gamble-George, J.C., Burgess, S., Dickson, A., Mamcarz, M., and Arendash, G.W
Published: July 1, 2008 in Alzheimer’s and Dementia, 4(4S Part 23): T760
DOI: 10.1016/j.jalz.2008.05.2373

Cotinine is neuroprotective against beta-amyloid toxicity

Authors: Burgess, S., Zeitlin, R., Gamble-George, J.C., and Echeverria Moran, V.
Published: July 1, 2008 in Alzheimer’s and Dementia, 4(4S Part 14): T466
DOI: 10.1016/j.jalz.2008.05.1396

"Pathways Toward Social Change: NPA Race and Ethnicity Equity Summit"

Authors: Gamble-George, J..
Published: March 2023 in The POSTDOCket
Online: https://www.nationalpostdoc.org/page/POSTDOCket_2101

Public Engagement with Biotechnology Inside and Outside the Classroom: Community-Focused Approaches

Authors: Jorge, J., Gamble-George, J., Danies, G., Hamm, R.L., and Porras, A.M.
Published: 2022 in GEN Biotechnology
DOI: 10.1089/genbio.2022.0024
PMID: 36032190

"Science Policy Careers: More to Them Than What Meets The Eye"

Authors: Gamble-George, J..
Published: December 2022 in The POSTDOCket
Online: https://www.nationalpostdoc.org/page/POSTDOCket_2003

"Going Beyond Brain Science to Impact Public Health"

Authors: Gamble-George, J..
Published: December 2021 in The POSTDOCket
Online: https://www.nationalpostdoc.org/page/POSTDOCket_1904

"Let Congress Know Postdocs Matter at the Rally For Medical Research"

Authors: Gamble-George, J..
Published: August 2019 in The POSTDOCket
Online: https://www.nationalpostdoc.org/page/postdocket_08186

"The PhD Project: A Means to Diversifying the Business Professoriate and Corporate America"

Authors: Gamble-George, J..
Published: July 2019 in The POSTDOCket
Online: https://www.nationalpostdoc.org/page/postdocket_0718

NextGen VOICES: Full Speed Ahead to the City on the Hill

Authors: Gamble-George, J.C., et al
Published: 2016 and Online Supplement in Science, 352(6288): 886-889
DOI: http://dx.doi.org/10.1126/science.aag1520

NextGen VOICES: Measures of Success

Authors: Gamble-George, J.C., et al
Published: 2016 and Online Supplement in Science, 352(6281): 28-30
DOI: http://dx.doi.org/10.1126/science.352.6281.28

NextGen VOICES: Definition of Success

Authors: Gamble-George, J.C., et al
Published: 2012 and Online Supplement in Science, 336(6077): 32-34
DOI: http://dx.doi.org/10.1126/science.336.6077.32

Article Image: “Signaling pathways, potential biomarkers, and therapeutic targets in preeclampsia (PE)”

Authors: Gamble-George, J..
Published: 2021, 30:2, p. 180, Fig. 1, in Journal of Women's Health, showing how placental ischemia-derived imbalance in proangiogenic and antiangiogenic factors, oxidative stress, and inflammation led to systemic vascular dysfunction reflected in hypertension and proteinuria in PE and potential targeted interventions, by Jasmina Varagic, Patrice Desvigne-Nickens, Joyonna Gamble-George, Lisa Hollier, Christine Maric-Bilkan, Megan Mitchell, Victoria L. Pemberton, and Nicole Redmond.

Article Image: “Pathophysiology of peripartum cardiomyopathy”

Authors: Gamble-George, J..
Published: 2021, 30:2, p. 181, Fig. 2, in Journal of Women's Health, showing the role of cathepsin D-cleaved 16-kDa prolactin fragment, microRNA146a, and decreased VEGF signaling and suppression of prolactin production by bromocriptine, by Jasmina Varagic, Patrice Desvigne-Nickens, Joyonna Gamble-George, Lisa Hollier, Christine Maric-Bilkan, Megan Mitchell, Victoria L. Pemberton, and Nicole Redmond.

Article Image: “Map of study sites in the PRECluDE consortium”

Authors: Gamble-George, J..
Published: 2020, 63:2, p. 86, Fig. 1, in Progress in Cardiovascular Disease, showing the PRECluDE consortium extending over twelve geographical areas throughout the U.S. at more than 30 healthcare organizations, by Joyonna Carrie Gamble-George, Christopher T. Longenecker, Allison R. Webel, David H. Au, Arleen F. Brown, Hayden Bosworth, Kristina Crothers, William E. Cunningham, Kevin A. Fiscella, Alison B. Hamilton, Christian D. Helfrich, Joseph A. Ladapo, Amneris Luque, Jonathan N. Tobin, Gail E. Wyatt, and Implementation Research to Develop Interventions for People Living with HIV (PRECluDE) Consortium.

Article Image: “Effects of COX-2 inhibition in the NIH assay”

Authors: Gamble-George, J..
Published: 2016, 5:e14137, p. 3, Fig. 1, in eLife, showing the novelty-induced hypophagia (NIH) test protocol with stress exposure and drug treatment time intervals, by Joyonna Carrie Gamble-George, Rita Baldi, Lindsay Halladay, Adrina Kocharian, Nolan Hartley, Carolyn Grace Silva, Holly Roberts, Andre Haymer, Lawrence J Marnett, Andrew Holmes, and Sachin Patel.

Article Image: “Effects of COX-2 inhibition in the elevated-plus maze”

Authors: Gamble-George, J..
Published: 2016, 5:e14137, p. 5, Fig. 2, in eLife, showing the elevated-plus maze (EPM) test protocol with stress exposure and drug treatment time intervals, by Joyonna Carrie Gamble-George, Rita Baldi, Lindsay Halladay, Adrina Kocharian, Nolan Hartley, Carolyn Grace Silva, Holly Roberts, Andre Haymer, Lawrence J Marnett, Andrew Holmes, and Sachin Patel.

Article Image: “Effects of COX-2 inhibition on contextual fear conditioning”

Authors: Gamble-George, J..
Published: 2016, 5:e14137, p. 6, Fig. 3, in eLife, showing the contextual fear conditioning protocol, by Joyonna Carrie Gamble-George, Rita Baldi, Lindsay Halladay, Adrina Kocharian, Nolan Hartley, Carolyn Grace Silva, Holly Roberts, Andre Haymer, Lawrence J Marnett, Andrew Holmes, and Sachin Patel.

Article Image: “Molecular architecture of endocannabinoid signaling at an excitatory synapse in the brain”

Authors: Gamble-George, J..
Published: 2013, 3:19, p. 2, Fig. 1, in Biology of Mood & Anxiety Disorders, showing how endocannabinoid signaling induces synaptic depression at excitatory synapses, by Matthew N. Hill and Sachin Patel.

Article Image: “cRaf-1 activation, inhibitors, and downstream signaling mechanisms”

Authors: Gamble-George, J..
Published: 2010, 9, p. 121, Fig. 1, in CNS & Neurological Disorders - Drug Targets, showing the activation of cRaf-1 by insults that stimulate oxidative stress and, consequently, the abnormal expression of proinflammatory and proapoptotic factors, which can be decreased by cRaf-1 inhibitors, by Sarah Burgess and Valentina Echeverria.

Article Image: “Chronic treatment with sorafenib inhibits cRaf-1 and ppERKs in the brain of Tg mice”

Authors: Gamble-George, J..
Published: 2009, 162:4, p. 1223, Fig. 1c, in Neuroscience, showing the phosphorylation of cRaf-1 at Ser 259 and Ser 338, by Valentina Echeverria, Sarah Burgess, Joyonna Gamble-George, Ross Zeitlin, Xiaoyang Lin, Chuanhai Cao, and Gary W. Arendash.

Article Image: “Molecular mechanisms underlying the beneficial actions of sorafenib in AD brains”

Authors: Gamble-George, J..
Published: 2009, 162:4, p. 1228, Fig. 6, in Neuroscience, showing how sorafenib, by inhibiting cRaf-1, decreases IKK complex activation, by Valentina Echeverria, Sarah Burgess, Joyonna Gamble-George, Ross Zeitlin, Xiaoyang Lin, Chuanhai Cao, and Gary W. Arendash.